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Updated: Aug 15, 2026

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
Diagnostic criteria for postconcussional syndrome after mild to moderate traumatic brain injury
Corwin Boake1, Stephen R McCauley, Harvey S Levin
1Baylor College of Medicine/University of Texas-Houston Medical School, Department of Physical Medicine and Rehabilitation, Houston, TX 77030-3405, USA. corwin.boake@uth.tmc.edu
Abstract:
This study evaluated the prevalence and specificity of diagnostic criteria for postconcussional syndrome (PCS) in 178 adults with mild to moderate traumatic brain injury (TBI) and 104 with extracranial trauma. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) and International Classification of Diseases (ICD-10) criteria for PCS were evaluated 3 months after injury. The results showed that prevalence of PCS was higher using ICD-10 (64%) than DSM-IV criteria (11%). Specificity to TBI was limited because PCS criteria were often fulfilled by patients with extracranial trauma. The authors conclude that further refinement of the DSM-IV and ICD-10 criteria for PCS is needed before these criteria are routinely employed.

