Related Experiment Video
Updated: Aug 15, 2026

Infinium Assay for Large-scale SNP Genotyping Applications
Published on: November 19, 2013
Y-SNP-genotyping - a new approach in forensic analysis
R Lessig1, M Zoledziewska, K Fahr
1Institute of Legal Medicine, University of Leipzig, Germany. Ruediger.Lessig@medizin.uni-leipzig.de
Abstract:
Y-chromosomal DNA polymorphisms, especially Y-STRs are well established in forensic routine case work. The STRs are used for identification in paternity deficiency cases and stain analysis with complicate mixtures of male and female DNA. In contrast, Y-chromosomal SNPs are a new tool in forensic investigations. At present, Y-SNPs are mainly used in molecular anthropology for evolutionary studies. Nevertheless, these markers could also provide very useful information for the analysis of forensic cases. The aim of the presented study was to test Y-SNP-typing for stain analyses using different methods-SNaPshot and MALDI-TOF MS. Both methods are based on the principle of minisequencing. The selected Y-SNP markers are suited to define the most important European haplogroups.
Related Concept Videos
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Single Nucleotide Polymorphisms-SNPs
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Modern Molecular Taxonomy
Sanger Sequencing
Pharmacogenomics: Identification of New Drug Targets

