[Myocardial function and rheologic properties of blood in multiple myeloma]

Echocardiographic and rheologic parameters were studied in 25 patients with multiple myeloma (MM). The lowering of the contractile function of the left ventricle myocardium was attended by disorders in blood rheologic properties characterized by increasing concentration of total protein and colloid-osmotic pressure, by a decrease in the hematocrit, red blood cell deformability, volume, and mean cell hemoglobin. It has been shown that rheologic and echocardiographic shifts play an important role in the pathogenesis of hyperviscous syndrome and in the development of circulation insufficiency in MM patients. Current corrective measures are necessary for abolishing this state.