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Rat-bite fever.

E van Nood1, S H A Peters

  • 1Department of Internal Medicine, Flevoziekenhuis, Almere, the Netherlands.

The Netherlands Journal of Medicine
|September 28, 2005
PubMed
Summary
This summary is machine-generated.

A woman with fever and rash was diagnosed with rat-bite fever caused by Streptobacillus moniliformis. Prompt treatment with clarithromycin led to a full recovery, highlighting the importance of considering this zoonotic disease.

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Area of Science:

  • Infectious Diseases
  • Zoonotic Infections
  • Microbiology

Background:

  • Rat-bite fever is a bacterial illness transmitted by rodents.
  • Streptobacillus moniliformis is a common cause of rat-bite fever.
  • Clinical presentation can include fever, rash, and joint pain.

Observation:

  • A 23-year-old woman presented with acute onset of fever, arthralgias, and a maculopapular rash.
  • The patient owned nine pet rats but denied any history of rodent bites.
  • Blood cultures revealed the presence of Streptobacillus moniliformis.

Findings:

  • The patient was diagnosed with Streptobacillus moniliformis infection, consistent with rat-bite fever.
  • Treatment with oral clarithromycin was initiated.

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  • The patient experienced a complete resolution of symptoms and clinical recovery.

    • Implications:

    • This case underscores the importance of considering rat-bite fever in patients with compatible symptoms, even without a clear history of a bite.
    • Early diagnosis and appropriate antibiotic therapy, such as clarithromycin, are crucial for favorable outcomes.
    • Pet rodents can serve as reservoirs for zoonotic pathogens, necessitating awareness among healthcare providers and the public.