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Updated: Aug 15, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Superior mesenteric artery (Wilkie's) syndrome as a result of cardiac cachexia
Archana Roy1, Justin J Gisel, Vivek Roy
1Mayo Clinic, Jacksonville, FL, USA.
Abstract:
Superior mesenteric artery (SMA) syndrome is a rare acquired disorder in which acute angulation of SMA causes compression of the third part of the duodenum between the SMA and the aorta, leading to obstruction. Loss of fatty tissue as a result of a variety of debilitating conditions is believed to be the etiologic factor causing the acute angulation. We report a case of an 86-year-old man with prolonged congestive heart failure and aortic stenosis in which SMA syndrome developed as a result of cardiac cachexia. Because of poor functional status and comorbidities, he was not a suitable candidate for decompressive surgery. Conservative treatment using a gastrostomy tube with jejunal extension led to improvement in nutritional status and resolution of symptoms.
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