Related Experiment Video
Updated: Jul 10, 2026

Analyzing Murine Schwann Cell Development Along Growing Axons
Published on: November 21, 2012
Neuronal nitric oxide synthase and nerve growth factor expression in the enteric nervous system
1Department of Veterinary Preclinical Sciences, University of Liverpool, Liverpool L69 7ZJ, UK. tswamy@liv.ac.uk
Abstract:
The role of nitric oxide (NO) in various systems of the body has gained prominence since the last decade. The dual role of NO either as a toxic or protective molecule depends on the concentrations of NO being produced, the isoform of NO synthase involved and the type of cell in which NO produced. The protective roles of NO appear to be mediated via cross talk between neurotrophic pathways. In view of this, in this paper, the role of NO in the enteric system is discussed with respect to neuronal nitric oxide synthase expression in neurons associated with the gut and the nerve growth factor and its receptor, tyrosine kinase A expression in the lamina epithelialis.
Related Concept Videos
Neural Regulation
Nitric Oxide Signaling Pathway
Physiology of Enteric Nervous System and Gut Health
Enteric Nervous System: Regulation of GI Motor Activity
During periods of fasting, the ENS initiates the migrating myoelectric complex, a program...
Nerve Supply of the GI Tract
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of the GI tract...

