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Updated: Aug 15, 2026
14:36
Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time
Published on: August 26, 2009
Fluorescence resonance energy transfer between a quantum dot donor and a dye acceptor attached to DNA
Dejian Zhou1, Joe D Piper, Chris Abell
1Nanoscience Centre, University of Cambridge, UK. dz209@cam.ac.uk
Chemical Communications (Cambridge, England)
|September 30, 2005
Abstract:
We show that direct coupling of a dye-labelled DNA (acceptor) to a quantum dot (QD) donor significantly reduces the donor-acceptor distance and improves the FRET efficiency: a highly efficient FRET (approximately 88%) at a low acceptor-to-donor ratio of 2 has been achieved at the single-molecule level.
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