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Updated: Aug 15, 2026

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 3, 2011
[Confocal microscopy of the cornea in photorefractive surgery]
J Javaloy1, M T Vidal, J M Ruiz-Moreno
1VISSUM, Instituto Oftalmológico de Alicante, Spain. jjavaloy@coma.es
Objective:
Corneal refractive surgery involves a range of techniques which have assumed a growing importance during the last few years. The advances of very different surgical methods and the early age of the majority of the patients subjected to surgery, limits our knowledge of the histopathologic changes in the operated corneas. For this reason, the development of any diagnostic tool which can permit us to improve our knowledge of the wound healing process would be of significant value. As we describe in our paper, confocal microscopy enables the assessment of the more important advantages for the study of corneal wound healing after refractive surgery: high magnification, harmless, and "in vivo", providing pathogenic information and lateral and axial definition not achievable with other exploration techniques.
Conclusion:
Confocal microscopy appears to be an essential tool for creating a global concept of quality in corneal refractive surgery.
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