[The influence of calcium folinate on the immunotoxicity of methanol]

The experiments on non-inbred rats showed that calcium folinate administered upon acute poisoning (0.5LD50) with methanol partly reduced the degree of suppression of the phagocyte metabolic activity of polymorphonuclear leukocytes, the T-dependent humoral immune response, the activity of natural killers, the antibody-dependent cell-mediated cytotoxicity, and the formation of the delay-type hypersensitivity, and completely restores the function of B-cells estimated using the T-independent antibody production.