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Herpes simplex esophagitis in the immunocompetent host.

S Kato1, R Yamamoto, S Yoshimitsu

  • 1Fukuoka Japan Self Defense Forces Hospital, Fukuoka, Japan.

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
|October 4, 2005
PubMed
Summary

This case study details herpes esophagitis and Mallory-Weiss syndrome in an immunocompetent individual. It highlights the importance of considering herpes esophagitis in severe odynophagia, even without immune compromise.

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Area of Science:

  • Gastroenterology
  • Virology
  • Infectious Diseases

Background:

  • Herpes esophagitis is typically seen in immunocompromised patients.
  • Mallory-Weiss syndrome involves esophageal tears, often from vomiting.

Observation:

  • A 26-year-old immunocompetent male presented with cold symptoms, fever, odynophagia, and hematemesis.
  • Endoscopy revealed esophageal ulcerations and a Mallory-Weiss tear.
  • Histology showed Cowdry type A intranuclear inclusions and HSV-1 positive staining.

Findings:

  • The patient was diagnosed with primary herpes simplex virus-1 (HSV-1) esophagitis.
  • This is the first reported case of herpes esophagitis with Mallory-Weiss syndrome in an immunocompetent host.
  • Serological tests confirmed primary HSV-1 infection.

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Implications:

  • Herpes esophagitis should be considered in immunocompetent patients presenting with severe odynophagia.
  • This case expands the known clinical spectrum of HSV-1 infections.
  • Early diagnosis and management are crucial for preventing complications.