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Boron and the kidney
Madeleine V Pahl1, B Dwight Culver, Nosratola D Vaziri
1Division of Nephrology and Hypertension, Department of Medicine, University of California, Irvine, CA, USA. mpahl@uci.edu
Summary
Boron exposure may harm kidney function. This review examines evidence on boron
Area of Science:
- Environmental Science
- Toxicology
- Nephrology
Background:
- Boron is a naturally occurring element found in food, water, and various industrial, cosmetic, and medical products.
- Recent observations suggest a link between boron exposure and chronic kidney disease in Southeast Asia.
Purpose of the Study:
- To review existing scientific literature on the renal effects of boron exposure.
- To evaluate the impact of both acute and chronic boron exposure on kidney function and structure.
Main Methods:
- Systematic review of published data.
- Analysis of studies involving human subjects and experimental animal models.
Main Results:
- Data on boron's effects on renal function and structure were compiled and analyzed.
- Evidence regarding the potential nephrotoxicity of boron was assessed.
Conclusions:
- The review synthesizes current knowledge on boron's impact on the kidneys.
- Further research may be needed to fully elucidate the relationship between boron exposure and kidney disease.