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Boron and the kidney.

Madeleine V Pahl1, B Dwight Culver, Nosratola D Vaziri

  • 1Division of Nephrology and Hypertension, Department of Medicine, University of California, Irvine, CA, USA. mpahl@uci.edu

Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
|October 4, 2005
PubMed
Summary

Boron exposure may harm kidney function. This review examines evidence on boron

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Area of Science:

  • Environmental Science
  • Toxicology
  • Nephrology

Background:

  • Boron is a naturally occurring element found in food, water, and various industrial, cosmetic, and medical products.
  • Recent observations suggest a link between boron exposure and chronic kidney disease in Southeast Asia.

Purpose of the Study:

  • To review existing scientific literature on the renal effects of boron exposure.
  • To evaluate the impact of both acute and chronic boron exposure on kidney function and structure.

Main Methods:

  • Systematic review of published data.
  • Analysis of studies involving human subjects and experimental animal models.

Main Results:

  • Data on boron's effects on renal function and structure were compiled and analyzed.
  • Evidence regarding the potential nephrotoxicity of boron was assessed.

Conclusions:

  • The review synthesizes current knowledge on boron's impact on the kidneys.
  • Further research may be needed to fully elucidate the relationship between boron exposure and kidney disease.

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