[Pathomorphological changes in the estrogenic syndrome of swine]

Epizootic, clinical and pathomorphological investigations were carried out on spontaneously arising oestrogen syndrome in swine following feeding with fodder mixture containing 35-63% maize in which the oestrogen substance z-2 (zearalenon) was found. Clinical symptoms and pathomorphological changes observed in the course of the disease are described. Varying in extent edematous processes were present in the regions around the anus, vulva, prepucium and the mammal complex. Uteruses were twice or thrice enlarged. Varying in size (pea grain to pigeon egg) cystose formations, sclerotic and atrophic changes were found in the ovaries of swine, which had suffered from vulvo-edema and were slaughtered after three months because they could not come in heat. Degenerative changes of the parenchymal organs, blood vessel disturbances in the uterine wall and various degenerative, atrophic and cystose changes in the ovarian folicules were histologically observed.