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Updated: Aug 15, 2026

The MultiBac Protein Complex Production Platform at the EMBL
Published on: July 11, 2013
Moonlighting vacuolar protease: multiple jobs for a busy protein
Faye M Rosin1, Naohide Watanabe, Eric Lam
1Biotech Center, Rutgers, The State University of New Jersey, 59 Dudley Road, New Brunswick, NJ 08901, USA.
Abstract:
In this Genomics Era with a wealth of annotated sequence data, it is easy to pigeonhole a protein into a particular function. However, Noa Matarasso et al. recently found a vacuolar protease that can also function as a transcription factor. This work illustrates that a protein can serve multiple roles in a cell, raising intriguing questions as to the extent that genomic information can be deciphered de novo.
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