Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renovascular hypertension: current concepts.

Vesna Garovic1, Stephen C Textor

  • 1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA.

Seminars in Nephrology
|October 6, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing biological understanding of cellular senescence with computational multiomics.

Nature genetics·2025
Same author

Blood Pressure Thresholds for Hypertension in Pregnancy and Future Cardiovascular Risk.

Mayo Clinic proceedings·2025
Same author

Postpartum counseling and interventions to reduce the risk of chronic kidney disease: back to the future.

Kidney international·2025
Same author

Socioeconomic Inequities in Preemptive Kidney Transplantation and Graft Survival: An Innovative Approach to Identifying Disparities in Kidney Transplantation.

Transplantation direct·2024
Same author

Role of chronic kidney disease and risk factors in preeclampsia.

Pregnancy hypertension·2024
Same author

Renovascular Disease and Mitochondrial Dysfunction in Human Mesenchymal Stem Cells.

Journal of the American Society of Nephrology : JASN·2024

Renovascular hypertension, caused by renal artery disease, often requires intensive blood pressure management. While medical therapy is common, revascularization may offer benefits, necessitating careful patient evaluation and ongoing monitoring for disease progression.

Area of Science:

  • Nephrology
  • Cardiology
  • Vascular Medicine

Background:

  • Renal artery occlusive disease is a significant cause of secondary hypertension.
  • Initial hemodynamic significance may be minimal, but disease can progress.
  • The renin-angiotensin-aldosterone system is crucial for initiating renovascular hypertension.

Purpose of the Study:

  • To review the mechanisms and management of renovascular hypertension.
  • To discuss the role of medical therapy versus revascularization.
  • To highlight the importance of intensive blood pressure and cardiovascular risk factor management.

Main Methods:

  • Review of experimental studies on renovascular hypertension initiation.
  • Analysis of clinical outcomes with medical therapy (ACE inhibitors, ARBs).

Related Experiment Videos

  • Discussion of prospective studies on renal revascularization benefits.

    • Main Results:

    • Angiotensin II triggers sustained hypertension via sodium retention, endothelial dysfunction, and oxidative stress.
    • Medical therapy can manage many unilateral renal artery disease cases long-term.
    • Prospective studies show limited but real blood pressure benefits from revascularization in atherosclerotic disease.

    Conclusions:

    • Management requires intensive blood pressure control and cardiovascular risk factor intervention.
    • Individualized risk-benefit assessment for revascularization is crucial.
    • Ongoing monitoring for restenosis and disease progression is essential post-treatment.