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Non-steroidal anti-inflammatory drug (NSAID)-induced colonic strictures and perforation: a case report
M M Aloysius1, P V Kaye, D N Lobo
1Section of Surgery, Division of Gastrointestinal Surgery, University Hospital, Queen's Medical Centre, E Floor West Block, Nottingham NG7 2UH, UK.
Abstract:
Although non-steroidal anti-inflammatory drug-induced colopathy is well described, colonic perforations complicating non-steroidal anti-inflammatory drug intake are rare. We report a patient with rheumatoid arthritis who was on long-term diclofenac and presented with early colonic stricture formation and a caecal perforation, which to the best of our knowledge, has only been reported once before. It is important to suspect this diagnosis in patients on non-steroidal anti-inflammatory drug therapy who present with an acute abdomen.
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