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Extramedullary plasmacytoma (EMP) of urinary bladder
K Matsumiya1, Y Kanayama, S Yamaguchi
1Department of Urology, Minoo City Hospital, Japan.
Urology
|July 1, 1992
Summary
A rare case of extramedullary plasmacytoma (EMP) in the urinary bladder was successfully treated with oral melphalan. The tumor and associated paraproteinemia regressed, with no recurrence observed over two years.
Area of Science:
- Oncology
- Urology
Background:
- Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm.
- Primary urinary bladder EMP is exceptionally uncommon, with few cases documented.
Observation:
- A patient presented with an isolated urinary bladder lesion and IgG-K paraproteinemia.
- The lesion was diagnosed as an extramedullary plasmacytoma.
Findings:
- Short-term oral melphalan treatment led to complete tumor regression.
- The IgG-K paraproteinemia also resolved following melphalan administration.
- No tumor recurrence was noted during a two-year follow-up period.
Implications:
- This case highlights the efficacy of melphalan in treating primary urinary bladder EMP.
- Successful management of this rare malignancy suggests a potential therapeutic option.
- Further research into optimal treatment strategies for urinary bladder EMP is warranted.