Clinical update of smooth muscle tumors of the uterus
Related Experiment Video
Updated: Aug 15, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
Leigh A Solomon1, Veronica L Schimp, Rouba Ali-Fehmi
1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wayne State University, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA. lsolomon@med.wayne.edu
Abstract:
Smooth muscle tumors of the uterus represent a spectrum of diseases that range from benign leiomyoma to malignant leiomyosarcoma. The leiomyoma is the most common of these neoplasms. Clinically, it is important to fully understand the differences in clinical presentation, biologic behavior, and management for patients with benign leiomyoma, smooth muscle tumors of uncertain malignant potential, and leiomyosarcoma. The goal of this review is to present the most recent information about common smooth muscle tumors of the uterus including their etiology, histopathology, radiographic and clinical presentations, and available treatment options.