Orthotopic transplantation of fresh ovarian cortex: a report of two cases
Jacques Donnez1, Jean Squifflet, Marie-Madeleine Dolmans
1Department of Gynecology, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium. donnez@gyne.ucl.ac.be
Objective:
To report two cases of orthotopic transplantation of fresh ovarian tissue.
Setting:
Academic hospital.
Patient(S):
Two patients with severe endometriosis, who underwent left oophorectomy for recurrent endometriosis.
Intervention(S):
Ovarian cortex was reimplanted in the heterolateral orthotopic site.
Result(S):
Biopsies of the grafted tissue were taken 3 months after reimplantation. Viable primordial follicles were found. The presence of a neovascular capillary network was demonstrated.
Conclusion(S):
Reimplantation of fresh ovarian cortex allows the survival of primordial follicles and may represent an alternative method for the preservation of ovarian cortex when oophorectomy is mandatory.
