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Intravenous gamma-globulin therapy in Diamond-Blackfan anemia
S Sumimoto1, M Kawai, Y Kasajima
1Department of Pediatrics, Sumitomo Hospital, Osaka, Japan.
Abstract:
Pure red cell aplasia (PRCA) is a rare disorder of erythrocyte production which is believed to have an autoimmune basis in most cases. Diamond-Blackfan anemia (DBA) is one type of congenital PRCA. Since PRCA has been reported to respond to intravenous gamma-globulin (IVGG) therapy, we administered IVGG to a 2 year old girl with DBA resistant to corticosteroids and observed slight therapeutic effect.