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Enamel defects in children with coeliac disease
E Farmakis1, J W Puntis, K J Toumba
1Dept Paediatric Dentistry, University of Leeds, England.
European Journal of Paediatric Dentistry
|October 12, 2005
Summary
Children with coeliac disease (CD) show a higher prevalence of enamel developmental defects in both primary and permanent teeth. This study highlights a significant association between CD and dental enamel abnormalities.
Area of Science:
- Pediatric Dentistry
- Gastroenterology
- Genetics
Background:
- Coeliac disease (CD) is an autoimmune disorder affecting the small intestine.
- Enamel developmental defects (EDDs) can arise from various systemic conditions.
- The relationship between CD and EDDs requires further investigation.
Purpose of the Study:
- To determine the prevalence of enamel developmental defects in children with a history of coeliac disease.
- To compare the incidence of EDDs in children with CD to a healthy control group.
- To analyze the association between coeliac disease and dental enamel abnormalities.
Main Methods:
- Recruited children diagnosed with coeliac disease (CD) and age/sex-matched controls.
- Utilized the DDE index to assess enamel defects and opacities.
- Recorded caries experience using dmf/dmfs and DMF/DMFS indices.
Main Results:
- Children with CD exhibited significantly more enamel defects in primary and permanent dentitions compared to controls.
- Opacities were statistically more prevalent in both primary and permanent teeth of children with CD.
- Conversely, dental caries were less prevalent in children with coeliac disease.
Conclusions:
- Coeliac disease is significantly associated with an increased prevalence of developmental enamel defects.
- The findings suggest a link between systemic health, specifically CD, and dental enamel formation.
- Further research may elucidate the underlying mechanisms connecting CD and EDDs.