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Enamel defects in children with coeliac disease

E Farmakis1, J W Puntis, K J Toumba

  • 1Dept Paediatric Dentistry, University of Leeds, England.

European Journal of Paediatric Dentistry
|October 12, 2005
PubMed

Insights

Children with coeliac disease (CD) show a higher prevalence of enamel developmental defects in both primary and permanent teeth. This study highlights a significant association between CD and dental enamel abnormalities.

Area of Science:

  • Pediatric Dentistry
  • Gastroenterology
  • Genetics

Background:

  • Coeliac disease (CD) is an autoimmune disorder affecting the small intestine.
  • Enamel developmental defects (EDDs) can arise from various systemic conditions.
  • The relationship between CD and EDDs requires further investigation.

Purpose of the Study:

  • To determine the prevalence of enamel developmental defects in children with a history of coeliac disease.
  • To compare the incidence of EDDs in children with CD to a healthy control group.
  • To analyze the association between coeliac disease and dental enamel abnormalities.

Main Methods:

  • Recruited children diagnosed with coeliac disease (CD) and age/sex-matched controls.
  • Utilized the DDE index to assess enamel defects and opacities.
  • Recorded caries experience using dmf/dmfs and DMF/DMFS indices.

Main Results:

  • Children with CD exhibited significantly more enamel defects in primary and permanent dentitions compared to controls.
  • Opacities were statistically more prevalent in both primary and permanent teeth of children with CD.
  • Conversely, dental caries were less prevalent in children with coeliac disease.

Conclusions:

  • Coeliac disease is significantly associated with an increased prevalence of developmental enamel defects.
  • The findings suggest a link between systemic health, specifically CD, and dental enamel formation.
  • Further research may elucidate the underlying mechanisms connecting CD and EDDs.
Abstract

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