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[Experience in the use of vaginal and intracervical enzaprost suppositories in preparation for labor]
To improve the efficacy of prelabor treatment of pregnant women with some obstetrical abnormalities, such as over-term pregnancy, AB0- and Rh-isosensitization, anemia, gestosis of the second half of pregnancy, vaginal and intracervical suppositories containing 0.1 mg of enzaprost were administered to 102 women for 1-5 days. In 30 (29.4%) cases such treatment induced spontaneous labor. In 64 (62.7%) women labor was induced by deoxy-amino oxytocin, and in 8 (7.8%) women this latter drug had to be administered repeatedly to induce labor. The babies born to the women under observation had the Apgar score of 6-10, 92 (90.2%) of them had the score of 8-10. No stillbirths or early infant mortality cases were recorded. Therefore prelabor treatment with vaginal or intracervical suppositories with enzaprost is effective and safe for both mother and newborn.
To improve the efficacy of prelabor treatment of pregnant women with some obstetrical abnormalities, such as over-term pregnancy, AB0- and Rh-isosensitization, anemia, gestosis of the second half of pregnancy, vaginal and intracervical suppositories containing 0.1 mg of enzaprost were administered to 102 women for 1-5 days. In 30 (29.4%) cases such treatment induced spontaneous labor. In 64 (62.7%) women labor was induced by deoxy-amino oxytocin, and in 8 (7.8%) women this latter drug had to be administered repeatedly to induce labor. The babies born to the women under observation had the Apgar score of 6-10, 92 (90.2%) of them had the score of 8-10. No stillbirths or early infant mortality cases were recorded. Therefore prelabor treatment with vaginal or intracervical suppositories with enzaprost is effective and safe for both mother and newborn.