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Updated: Aug 15, 2026

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
Published on: February 27, 2018
[Amisulpride in Huntington's disease]
Carsten Saft1, Jürgen Andrich, Peter H Kraus
1Neurologische Klinik der Ruhr-Universität Bochum, St. Josef-Hospital, Huntington Zentrum NRW, Bochum. carsten.saft@cityweb.de
Objectives:
Amisulpride is a substituted benzamide derivative with atypical antipsychotic properties and low side effects.
Method:
We report four cases of patients with clinically and genetically established Huntington's disease and signs of psychosis who were treated with Amisulpride.
Results:
Two patients developed extrapyramidal side effects due to the treatment. The antipsychotic therapy of all patients was effective.
Discussion:
Due to degeneration of striatal neurons patients suffering from Huntington's disease react early with development of extrapyramidal side effects after therapy with amisulpride.
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