Total body water volume for white children and adolescents and anthropometric prediction equations: the Fels

William C Chumlea1, Christine M Schubert, Nicholas V Reo

  • 1Department of Community Health, Wright State University School of Medicine, Dayton, OH 45420, USA. cameron.chumlea@wright.edu

Kidney International
|October 14, 2005
PubMed

Insights

This study provides updated total body water (TBW) prediction equations for children aged 8-20. New equations account for sex and maturation, improving clinical management for pediatric renal patients.

Area of Science:

  • Pediatric physiology
  • Body composition analysis
  • Biostatistics

Background:

  • Limited data exists on total body water (TBW) volume in children.
  • New prediction equations are crucial for managing pediatric renal insufficiency and dialysis patients.

Purpose of the Study:

  • To develop sex-specific prediction equations for total body water (TBW) in white children aged 8 to 20 years.
  • To provide updated reference means for TBW in this demographic.

Main Methods:

  • Utilized mixed longitudinal data from 124 boys and 116 girls (ages 8-20).
  • Measured TBW volume using deuterium nuclear magnetic resonance spectroscopy.
  • Employed random effects models and regression analysis for equation development.

Main Results:

  • Boys exhibited significantly greater mean TBW volumes than girls across most ages.
  • TBW was significantly associated with age and maturation in both sexes.
  • Developed sex-specific prediction equations: Boys: TBW = -25.87 + 0.23(stature) + 0.37(weight); Girls: TBW = -14.77 + 0.18(stature) + 0.25(weight).

Conclusions:

  • Presented means for TBW in white children (8-20 years), noting fatness influences TBW percentage.
  • The developed TBW prediction equations demonstrate improved accuracy over existing models.
Abstract

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