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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Total body water volume for white children and adolescents and anthropometric prediction equations: the Fels
William C Chumlea1, Christine M Schubert, Nicholas V Reo
1Department of Community Health, Wright State University School of Medicine, Dayton, OH 45420, USA. cameron.chumlea@wright.edu
Insights
This study provides updated total body water (TBW) prediction equations for children aged 8-20. New equations account for sex and maturation, improving clinical management for pediatric renal patients.
Area of Science:
- Pediatric physiology
- Body composition analysis
- Biostatistics
Background:
- Limited data exists on total body water (TBW) volume in children.
- New prediction equations are crucial for managing pediatric renal insufficiency and dialysis patients.
Purpose of the Study:
- To develop sex-specific prediction equations for total body water (TBW) in white children aged 8 to 20 years.
- To provide updated reference means for TBW in this demographic.
Main Methods:
- Utilized mixed longitudinal data from 124 boys and 116 girls (ages 8-20).
- Measured TBW volume using deuterium nuclear magnetic resonance spectroscopy.
- Employed random effects models and regression analysis for equation development.
Main Results:
- Boys exhibited significantly greater mean TBW volumes than girls across most ages.
- TBW was significantly associated with age and maturation in both sexes.
- Developed sex-specific prediction equations: Boys: TBW = -25.87 + 0.23(stature) + 0.37(weight); Girls: TBW = -14.77 + 0.18(stature) + 0.25(weight).
Conclusions:
- Presented means for TBW in white children (8-20 years), noting fatness influences TBW percentage.
- The developed TBW prediction equations demonstrate improved accuracy over existing models.
Background:
There are few studies of total body water (TBW) volume in children. Such studies are needed, as are new prediction equations for the clinical management of children with renal insufficiency and those receiving dialysis.
Methods:
Mixed longitudinal data were from 124 white boys and 116 white girls 8 to 20 years of age. TBW volume was measured by deuterium nuclear magnetic resonance spectroscopy, and random effects models were used to determine patterns of change over time. Sex-specific TBW prediction equations were developed using regression analysis.
Results:
Boys had significantly greater (P < 0.05) mean TBW volumes than girls at all but 3 ages. TBW was significantly (P < 0.05) associated with age and maturation in the boys and the girls. In boys, mean TBW/WT varied from 0.55 to 0.59, while in the girls the mean declined from 0.53 to 0.49 by 16 years of age. Boys had significantly larger means for TBW/WT than girls, who had a significant, slight negative trend with age. The prediction equations were TBW = -25.87 + 0.23 (stature) + 0.37 (weight) for boys and TBW =-14.77 + 0.18 (stature) + 0.25 (weight) for girls.
Conclusion:
Means are provided for TBW in white children from 8 to 20 years of age, whose average fatness affected the percentage of TBW in body weight. These updated TBW prediction equations perform better than those available from the past.
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