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Effect of haemodialysis on signal-averaged electrocardiogram P-wave parameters

Andrzej J Jaroszyński1, Andrzej Głowniak, Tomasz Sodolski

  • 1Clinic of Nephrology, Medical University of Lublin, Lublin, Poland. JaroszynskiAJ@interia.pl

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|October 14, 2005
PubMed

Insights

Hemodialysis (HD) patients show abnormal P-wave signal-averaged electrocardiogram (SAECG) parameters, which improve after HD. Age, volume status, and anemia influence these SAECG findings in HD patients.

Area of Science:

  • Cardiology
  • Nephrology
  • Biomedical Engineering

Background:

  • P-wave signal-averaged electrocardiogram (SAECG) is a non-invasive tool for assessing paroxysmal atrial fibrillation risk.
  • Hemodialysis (HD) may impact cardiac electrical activity, necessitating evaluation of SAECG parameters in HD patients.

Purpose of the Study:

  • To investigate the effect of the hemodialysis (HD) process on SAECG parameters in HD patients.
  • To identify factors influencing SAECG parameters in this patient group.

Main Methods:

  • Forty-seven HD patients without significant cardiac disease underwent SAECG pre- and post-dialysis.
  • Extracellular body water (ECW) and biochemical measurements were performed.
  • Filtered P-wave duration (FPD) and RMS voltage of the final 20 ms (RMS20) were analyzed.

Main Results:

  • HD patients exhibited higher pre- and post-dialysis FPD and lower pre- and post-dialysis RMS20 compared to controls.
  • Hemodialysis significantly decreased FPD and increased RMS20.
  • Age, ECW/kg body weight, and hemoglobin levels were independent predictors of FPD, but not RMS20.

Conclusions:

  • P-wave SAECG parameters are abnormal in many HD patients but improve post-dialysis.
  • Patient age, volume status, and anemia significantly influence SAECG parameters in HD patients.
Abstract

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