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Updated: Aug 15, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Effect of muscular contraction on magnetization transfer detected at 1.5 T
1Department of Radiology, Kyushu University Hospital at Beppu, 4546 Tsurnihara, Tsurumi, Beppu, Oita 874-0838, Japan. hatake@beppu.kyushu-u.ac.jp
Abstract:
The effect of rigor (formation of actomyosin complexes) on magnetization transfer was observed with a 1.5 T clinical magnetic resonance (MR) imaging system. The magnetization transfer ratio of chemically skinned (calcium-sensitive) muscle fiber preparations increased much more in a rigor state than in a relaxed state, while that of calcium-insensitive fiber preparations and solutions showed no difference. These results suggest that the formation of actomyosin complexes increased the magnetization transfer ratio. A clinical MR system is not only effective for medical imaging, but also has the potential to demonstrate physiological characteristics.
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