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Updated: Aug 15, 2026

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)
Published on: March 14, 2013
Fusion of mass spectrometry-based metabolomics data
Age K Smilde1, Mariët J van der Werf, Sabina Bijlsma
1TNO Quality of Life, P. O. Box 360, 3700 AJ Zeist, The Netherlands. smilde@voeding.tno.nl
Abstract:
A general method is presented for combining mass spectrometry-based metabolomics data. Such data are becoming more and more abundant, and proper tools for fusing these types of data sets are needed. Fusion of metabolomics data leads to a comprehensive view on the metabolome of an organism or biological system. The ideas presented draw upon established techniques in data analysis. Hence, they are also widely applicable to other types of X-omics data provided there is a proper pretreatment of the data. These issues are discussed using a real-life metabolomics data set from a microbial fermentation process.
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