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Related Experiment Videos

Baylisascariasis.

Patrick J Gavin1, Kevin R Kazacos, Stanford T Shulman

  • 1Microbiology and Infectious Diseases Research, Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, Evanston, IL 60201, USA. pgavin@enh.org

Clinical Microbiology Reviews
|October 15, 2005
PubMed
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Baylisascaris procyonis, the raccoon roundworm, causes severe neural larva migrans in humans. Prevention is key, as treatment is often ineffective for this dangerous parasitic infection.

Area of Science:

  • Veterinary Medicine
  • Parasitology
  • Public Health

Background:

  • Baylisascaris procyonis (raccoon roundworm) is a common cause of larva migrans in animals.
  • It increasingly causes severe neural larva migrans in children and ocular larva migrans in adults.
  • Human infection occurs through ingestion of B. procyonis eggs from raccoon feces.

Purpose of the Study:

  • To highlight the severe neurological and ocular manifestations of Baylisascaris procyonis infection in humans.
  • To emphasize the aggressive nature and poor prognosis of B. procyonis neural larva migrans.
  • To underscore the importance of prevention due to limited treatment efficacy.

Main Methods:

  • Review of clinical and epidemiological data on human baylisascariasis.

Related Experiment Videos

  • Analysis of B. procyonis larval migration patterns and growth within the central nervous system.
  • Assessment of risk factors associated with human infection.

    • Main Results:

    • B. procyonis exhibits aggressive migration, particularly into the central nervous system, with continued larval growth.
    • Neural larva migrans typically presents as fulminant eosinophilic meningoencephalitis with a grave prognosis.
    • Contact with raccoon feces and geophagia/pica are significant risk factors for human infection.

    Conclusions:

    • Widespread raccoon populations and environmental contamination pose a substantial risk for human baylisascariasis.
    • Early diagnosis and effective treatment remain challenging, making prevention paramount.
    • Public health measures focusing on preventing exposure to raccoon feces are crucial.