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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Biphasic interaction of gamma-globulin with copper cations

S B Cheknev1, E E Babaeva, M S Zharkova

  • 1Laboratory of Cell-Cell Interactions, NF Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow. cheknev@riem.ru

Bulletin of Experimental Biology and Medicine
|October 15, 2005
PubMed
Summary

Copper interacts with human serum gamma-globulin, altering its structure and optical properties. These findings suggest bivalent metal cations may influence immunoactive serum protein conformations.

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