Related Experiment Videos
Platelets and blood vessels: the adhesion event
1Hematology Section, Seattle Veterans Hospital, WA.
Circulating blood platelets attach to damaged blood vessels by specific adhesion molecules. In the human arterial circulation, a unique 'shear-dependent' mechanism governs adhesion by a single receptor-ligand (glycoprotein Ib-von Willebrand factor) pair. Here, Gerald Roth reviews recent data that provide insights into the functions of these molecules.
Circulating blood platelets attach to damaged blood vessels by specific adhesion molecules. In the human arterial circulation, a unique 'shear-dependent' mechanism governs adhesion by a single receptor-ligand (glycoprotein Ib-von Willebrand factor) pair. Here, Gerald Roth reviews recent data that provide insights into the functions of these molecules.