Related Experiment Video
Updated: Aug 15, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Acute transverse myelitis following dengue virus infection
Raymond C S Seet1, Erle C H Lim, Einar P V Wilder-Smith
1Division of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. raymond_seet@nus.edu.sg
Abstract:
The spinal cord is infrequently affected following dengue virus infection. We report a case of transverse myelitis that developed 2 weeks after acute dengue infection and review the literature to elucidate the pathogenesis of spinal cord involvement in dengue infection. We postulate that temporal factors may play a role in the different clinical manifestations, i.e. that acute parainfectious dengue infection presents with flaccid paralysis, whereas late-stage (postinfectious) dengue infection, presents with spastic weakness. Further studies need to be performed to elucidate the mechanisms of spinal neurological damage in dengue.
Related Concept Videos
Arboviral Encephalitis
Encephalitis ll: Pathophysiology
Encephalitis l: Introduction
Poliomyelitis
Rabies
Viral Meningitis
