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Cyclopeptide alkaloids from Scutia buxifolia Reiss and their antimicrobial activity
Ademir F Morel1, Graciela Maldaner, Vinicius Ilha
1Departamento de Química (NPPN), Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil. afmorel@base.ufsm.br
Abstract:
The present study reports a cyclopeptide alkaloid, scutianine M, isolated from the methanolic root bark extract of Scutia buxifolia Reiss (Rhamnaceae) along with six known compounds, scutianines-B, -C, -D, -E, -F, and scutianene D. Its structure was established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. As part of a study of the bioactive compounds of medicinal plants from southern Brazil, we also compared the antimicrobial activity of the isolated compounds towards Gram (+), Gram (-) bacteria, and yeasts.
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