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Optic disk edema associated with sudden-onset anterior uveitis
Blythe E Monheit1, Russell W Read
1Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
American Journal of Ophthalmology
|October 18, 2005
Summary
Optic disk edema (ODE) associated with sudden-onset anterior uveitis resolved slowly, often lagging behind uveitis resolution by up to six weeks. Cranial imaging did not reveal abnormalities causing the optic nerve swelling.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
Background:
- Sudden-onset anterior uveitis can present with optic disk edema (ODE).
- The clinical characteristics and course of ODE in this context require further description.
Purpose of the Study:
- To describe the clinical characteristics and course of optic disk edema (ODE) associated with isolated sudden-onset anterior uveitis.
Main Methods:
- Retrospective case series of patients with sudden-onset anterior uveitis and concomitant ODE.
- Reviewed eleven eyes of seven patients seen between August 2001 and November 2002.
- Assessed optic nerve function and performed cranial magnetic resonance imaging.
Main Results:
- Optic nerve function remained intact in all cases.
- Cranial MRI was normal in most patients or revealed unrelated abnormalities.
- Resolution of anterior uveitis occurred over a mean of 36 days, with ODE resolution lagging by a mean of 20 days.
Conclusions:
- Optic disk edema resolution lagged behind anterior uveitis resolution by up to six weeks.
- No causative abnormalities for ODE were identified on cranial imaging in this cohort.