Related Experiment Video
Updated: Jul 25, 2025
10:33
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
2.7K
Posterior Herpetic Uveitis: A Comprehensive Review.
Andrea Servillo1,2, Alessandro Berni1,2, Alessandro Marchese1,2
1Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ocular Immunology and Inflammation
|June 26, 2023
Summary
Posterior herpetic uveitis presents with diverse clinical signs caused by herpes simplex, varicella zoster, and cytomegalovirus. Recognizing these ocular manifestations aids in early diagnosis of herpetic uveitis.
Area of Science:
- Ophthalmology
- Virology
- Immunology
Background:
- Posterior herpetic uveitis is an inflammatory condition affecting the back of the eye.
- Herpes simplex virus (HSV), varicella zoster virus (VZV), and cytomegalovirus (CMV) are common causative agents.
- Understanding the varied clinical presentations is crucial for diagnosis and management.
Purpose of the Study:
- To summarize and illustrate the primary clinical presentations of posterior herpetic uveitis.
- To highlight the diverse ocular manifestations associated with different herpetic viruses.
Main Methods:
- This study is based on a narrative review of existing literature.
- Clinical presentations of posterior herpetic uveitis were analyzed.
Main Results:
- HSV and VZV can lead to acute retinal necrosis, progressive outer retinal necrosis, and non-necrotizing herpetic retinopathies.
- CMV is linked to fulminant retinitis, indolent/granular retinitis, and frosted branch angiitis.
- Clinical findings often correlate with specific risk factors and host immune profiles.
Conclusions:
- Herpetic viruses induce a spectrum of posterior uveitis clinical findings.
- Ocular manifestations and host immunology can help differentiate herpetic entities pre-diagnosis.
- Early recognition of clinical signs aids in timely laboratory confirmation and treatment.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
481
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
481
01:25Glaucoma: Overview
630
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
630
01:28Angle Closure Glaucoma: Treatment
577
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
577
01:26Nephrotic Syndrome II : Assessment and Medical Management
10
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
10