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[Long-term results of radiofrequency-assisted posterior transverse cordotomy in a rabbit model]
Lokman Uzun1, Mehmet Birol Uğur, Fikret Cinar
1Department of Otolaryngology, Medicine Faculty of Karaelmas University, Zonguldak, Turkey. luzun99@yahoo.com
Objectives:
We evaluated the long-term results of radiofrequency-assisted posterior transverse cordotomy in a rabbit model.
Study Design:
Ten healthy New Zealand rabbits were subjected to videolaryngoscopic examination following intraperitoneal anesthesia with 20 mg/kg thiopental. After local infiltration anesthesia with lidocaine, a laryngofissure procedure and exposition of the vocal cords were carried out and posterior transverse cordotomy was performed to the right vocal cord in the cutting mode using radiofrequency waves (Ellman Surgitron). The thyroid cartilage was closed in anatomic position and the rabbits were followed-up for three months, after which videolaryngoscopic examination was repeated. The rabbits were then sacrificed for histopathologic examination.
Results:
At the end of the follow-up period, videolaryngoscopic examination showed neo-cordogenesis in the right vocal cord region. Histological examination showed closure of the operation site by granulation tissue and fibrosis.
Conclusion:
The opening created in the rabbit larynx using radiofrequency was filled by granulation tissue and fibrosis in the long-term.
