Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Librarians, crystal structures and drug design.

Frank H Allen¹, Robin Taylor

¹Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, UKCB2 1EZ. allen@ccdc.cam.ac.uk

Chemical Communications (Cambridge, England)

|October 18, 2005

Summary

The Cambridge Structural Database (CSD) now contains 355,000 crystal structures, crucial for drug design and pharmaceutical formulation. Data accuracy in the CSD ensures the reliability of chemical research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Creative Futures in Education: Building 'Imagination Infrastructures' for Microbiology and Beyond.

Microbial biotechnology·2025

Same author

Correspondence on "Taxonomy of Chemical Bondings: Opportunities and Challenges".

Angewandte Chemie (International ed. in English)·2025

Same author

Strengthening the Capacity of Service Providers to Reduce the Impact of the COVID-19 Pandemic on African, Caribbean, and Black Communities: Protocol for the COVID-19 African, Caribbean, and Black Providers Project 2.0 Implementation and Evaluation.

JMIR research protocols·2025

Same author

Oculomics: A Crusade Against the Four Horsemen of Chronic Disease.

Ophthalmology and therapy·2024

Same author

Molecular Dynamics Study of the Aggregation Behavior of <i>N</i>,<i>N</i>,<i>N</i>',<i>N</i>'-Tetraoctyl Diglycolamide.

The journal of physical chemistry. B·2022

Same author

Sustainability and Justice: Challenges and Opportunities for an Open STEM Education.

CBE life sciences education·2022

Area of Science:

Crystallography
Materials Science
Drug Discovery

Background:

The Cambridge Structural Database (CSD) is a comprehensive repository of organic and metal-organic crystal structures.
It currently holds 355,000 validated and annotated structures.
Accurate crystal structure data is fundamental for advancing chemical research and pharmaceutical development.

Purpose of the Study:

To highlight the scale and importance of the Cambridge Structural Database (CSD).
To emphasize the role of the CSD in rational drug design.
To underscore the significance of data accuracy and completeness for pharmaceutical ingredient formulation.

Main Methods:

Data acquisition and validation of published crystal structures.
Chemical annotation and organization of structural data.
Utilizing the CSD for searching and analysis in drug design.

Main Results:

The CSD now comprises 355,000 published crystal structures.
The database is actively used in rational drug design.
CSD data is increasingly relevant for pharmaceutical active ingredient formulation.

Conclusions:

The CSD is an invaluable resource for the scientific community.
The integrity of crystal structure data in the CSD is paramount for its applications.
Continued curation and expansion of the CSD will support future innovations in chemistry and medicine.

Related Experiment Videos