Related Experiment Videos
Effects of the clotting process on endothelium-dependent relaxation of human middle cerebral artery
1Department of Pharmacology, Yerevan Medical Institute, Armenia, Russia.
Clotted blood decreased acetylcholine-induced relaxations of strips of human middle cerebral artery precontracted with noradrenaline, although histologically the endothelial layer was preserved. This effect was not prevented by catalase, superoxide dismutase or aspirin. Nifedipine reduced the decrease in acetylcholine-induced relaxation.
Clotted blood decreased acetylcholine-induced relaxations of strips of human middle cerebral artery precontracted with noradrenaline, although histologically the endothelial layer was preserved. This effect was not prevented by catalase, superoxide dismutase or aspirin. Nifedipine reduced the decrease in acetylcholine-induced relaxation.