A tetrapeptide-based method for polyproline II-type secondary structure prediction

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A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Peter K Vlasov1, Anna V Vlasova, Vladimir G Tumanyan

  • 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. vlasov@imb.ac.ru

Proteins
|October 19, 2005
PubMed

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Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
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Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
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