Related Experiment Video
Updated: Aug 15, 2026

Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle
Published on: December 22, 2023
Formation of large DNA aggregates induced by spermidine
1SVBL, Graduate School of Science and Engineering, Ibaraki University, 4-12-1 Nakanarusawa, Hitachi, Ibaraki 316-8511, Japan. kuramochi.hidetoshi@nies.go.jp
Abstract:
The formation of large DNA aggregates induced by spermidine was investigated by UV absorptiometry and polarizing microscopy. The present results reveal that it is stepwise and involves the following morphological variations: fiber, fiber bundles, and a highly condensed phase. Furthermore, the influence of DNA concentration on not only the spermidine concentration required for the DNA aggregation but also the concentration of free spermidine during the aggregation is analyzed.
Related Concept Videos
Single-Strand DNA Binding Proteins
Restarting Stalled Replication Forks
DNA Damage can Stall the Cell Cycle

