Teflon bags for 5-day storage of platelet concentrates (PC) from cell separator

There exist no data yet about platelet storage in teflon bags. Therefore, a paired study has been performed to evaluate their suitability for the 5 days storage of platelet concentrates (PC) from the cell separator Fresenius AS-104. The PC's of the AS-104 were stored in teflon as well as in polyolefin bags each (PL-732). In addition, PC's of the Baxter CS-3000 were stored in PL-732. PH, cell counts, platelet morphology, aggregation, adherence and ADP/ATP concentration, plasma beta TG, glucose, lactate and thrombin-antithrombin III complexes were investigated at day 0, 3 and 5 of storage. The results show that the teflon bags are quite suitable for 5 day storage of the PC's. But the functional superiority of fresh PC's from the AS-104 seemed to be reduced by storage in teflon bags compared to storage in PL-732. The unfavorable size and geometry of the teflon bags used could have been the cause. Therefore, size and geometry were consequently changed in the meantime.