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Updated: Aug 15, 2026
13:09
Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
Published on: March 3, 2023
Development of new dosimetry using extended DNA fibers
Sachihiro Matsunaga1, Kazutaka Ohshio, Erimu Harada
1Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Journal of Bioscience and Bioengineering
|October 20, 2005
Abstract:
We applied fluorescent microscopy to monitor the damage of DNA upon exposure to gamma radiation. Our developed dosimetry demonstrated that the number of breaks in DNA is proportional to the dose of the irradiation but is not dependent on dose rate of the irradiation and the GC content of DNA.
