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Updated: Aug 15, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Assessment of the calf vein cross section change during stand-test after a 90 day bed rest by echography
Objective:
To evaluate the contribution of the calf veins distension during stand test to orthostatic intolerance (OI).
Method:
The population consisted of a control group (Co, n=9) and an exercise (Fly-Wheel) counter-measure group (CM, n=9). Calf vein cross section area was assessed by echography during pre and post HDT stand-tests.
Results:
Tibial, and muscular vein section at rest did not change during HDT in both groups. From supine to standing, the Tibial and muscular vein section increased significantly more at post HDT in non tolerant subjects, compare to pre HDT (tibial V: +122% from pre-HDT, muscular V: +145% p<005). In tolerant subjects the vein cross section increase from supine to stand was similar pre and post HDT.
Conclusion:
Fly-Wheel CM, did not reduce OI. High calf vein section increase at post-HDT stand-test compare to pre-HDT was significantly correlated with OI but not with CM.
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