Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changes in Doppler mitral inflow patterns during parabolic flight.

E G Caiani1, G Asquer, M Turiel

  • 1Biomedical Eng. Dept., Politecnico di Milano, Milano, Italy. caiani@biomed.polimi.it

Journal of Gravitational Physiology : a Journal of the International Society for Gravitational Physiology
|October 21, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-duration human spaceflight induces atrophy in the left ventricular papillary muscles.

NPJ microgravity·2025
Same author

Echocardiography guided management of atrial fibrillation.

Intensive care medicine·2025
Same author

State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2025
Same author

Analysis of the Sustainable Development Goal 3 index for Italian municipalities.

Public health·2024
Same author

Analysis of changes in cardiac circadian rhythms of RR and QT induced by a 60-day head-down bed rest with and without nutritional countermeasure.

European journal of applied physiology·2020
Same author

Prehospital triage of acute aortic syndrome using a machine learning algorithm.

The British journal of surgery·2020
Same journal

Hypergravity effects on pregnancy and parturition.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2013
Same journal

Characteristics of the parallel-plate flow chamber for mechanical stimulation of bone cells under microgravity.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2009
Same journal

From the first dog to the last monkey in space.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2008
Same journal

Columbus, the European Physiology Modules Facility and CADMOS.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2008
Same journal

Abdominal and fetal echography tele-operated in several medical centres sites, from an expert center, using a robotic arm & telephone or satellite link.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2008
Same journal

WISE-2005: developing a non-invasive method to monitor cardiovascular deconditioning.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology·2008
See all related articles

Parabolic flights reveal microgravity alters mitral inflow velocity patterns in standing subjects. These changes in heart function during spaceflight simulation highlight unique physiological responses.

Area of Science:

  • Cardiovascular Physiology
  • Space Medicine
  • Echocardiography

Background:

  • Understanding cardiovascular adaptation to altered gravity is crucial for space exploration.
  • Mitral inflow velocity patterns reflect cardiac loading conditions.

Purpose of the Study:

  • To investigate the impact of acute changes in gravitational loading on mitral inflow velocity patterns.
  • To assess cardiovascular responses during microgravity and hypergravity phases of parabolic flight.

Main Methods:

  • Transthoracic Doppler echocardiography was used to record mitral inflow velocity.
  • Pulsed-Doppler imaging was performed on 11 healthy subjects during parabolic flights.
  • Data were analyzed for alterations during normogravity, microgravity, and hypergravity phases in standing and supine positions.

Related Experiment Videos

Main Results:

  • Significant alterations in mitral inflow velocity parameters were observed during microgravity in the standing position (p<0.05).
  • Changes were noted in several Doppler-derived inflow parameters, indicating altered diastolic function.
  • No significant alterations were consistently reported in the supine position.

Conclusions:

  • Acute microgravity significantly affects mitral inflow velocity patterns, particularly in the upright posture.
  • These findings underscore the sensitivity of cardiac diastolic function to gravitational changes.
  • Further research is needed to understand long-term implications for astronauts.