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Published on: October 20, 2017
[Natural history and management of mycotic intracranial aneurysm]
P Koch1, H A Desal, E Auffray-Calvier
1Service de Neuroradiologie Diagnostique et Interventionnelle, Hôpital G&R Laënnec, CHU de Nantes, Bd Jacques Monod - St Herblain, 44093 Nantes Cedex 1, France.
Introduction:
mycotic intracranial aneurysms are a rare complication of infectious endocarditis. We report four cases of patients with endocarditis, complicated by an acute stroke, revealing a mycotic intracranial aneurysm.
Patients And Methods:
four men (aged range 24 to 63 year old) were admitted for endocarditis, complicated by ischemic stroke in two cases and hemorrhagic stroke in the two other cases, including one with subarachnoid hemorrhage. Neuroimaging disclosed a mycotic cerebral aneurysm in all four cases.
Discussion:
we will discuss the natural history and the management of mycotic intracranial aneurysm based on a review of the literature and our experience. Three therapeutic options are possible: medical treatment, surgery and endovascular embolisation.
Conclusion:
management of mycotic intracranial aneurysms is still controversial, frequently requiring a multidisciplinary strategy with priority given to endovascular interventions.
Insights
Mycotic intracranial aneurysms, a rare complication of infectious endocarditis, can cause acute stroke. Early diagnosis and a multidisciplinary approach, prioritizing endovascular interventions, are crucial for managing these complex cases.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Surgery
Background:
- Mycotic intracranial aneurysms are uncommon but serious complications of infectious endocarditis.
- Infectious endocarditis can lead to cerebrovascular events, including ischemic and hemorrhagic strokes.
Observation:
- This study reports on four male patients diagnosed with infectious endocarditis.
- All patients presented with acute stroke (ischemic or hemorrhagic), with one experiencing subarachnoid hemorrhage.
- Neuroimaging confirmed the presence of a mycotic cerebral aneurysm in all four cases.
Findings:
- The cases highlight the association between endocarditis, stroke, and mycotic intracranial aneurysms.
- Management strategies for mycotic intracranial aneurysms include medical treatment, surgery, and endovascular embolization.
Implications:
- The optimal management of mycotic intracranial aneurysms remains debated, often necessitating a collaborative, multidisciplinary approach.
- Endovascular interventions are frequently favored as a primary treatment modality for these aneurysms.
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