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Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila
Published on: October 1, 2011
Allometric scaling of biological rhythms in mammals
Bruno Günther1, Enrique Morgado
1Professor Emeritus of Physiology and Physiopathology, Universidad de Concepción, Concepción, Chile,
Abstract:
A wide spectrum of cyclic functions in terrestrial mammals of different size, from the 3-gram shrew to the 3-ton elephant, yields an allometric exponent around 0.25, which is correlated--as a kind of common denominator--with the specific metabolic rate. Furthermore, the applicability of these empirical findings could be extrapolated to chronological events in the sub-cellular realm. On the other hand, the succession of growth periods (T98%) until sexual maturity is reached also follows the 1/4 power rule. By means of Verhulst's logistic equation, it has been possible to simulate three different biological conditions, which means that by modifying the numerical value of only one parameter, revertible physiological and pathological states can be obtained, as for instance isostasis, homeostasis and heterostasis.
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