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Bacterial Protein Maturation

Bacterial Protein Maturation

Bacterial protein maturation is a tightly regulated process that ensures newly synthesized polypeptides achieve correct functional conformations. This maturation involves a series of modifications, folding events, and quality control steps, often assisted by specialized chaperone proteins.N-Terminal ModificationsThe maturation of bacterial polypeptides begins cotranslationally as the polypeptide exits the ribosome. The first amino acid, N-formylmethionine (fMet), is typically modified at the...

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Related Experiment Video

Updated: Jul 6, 2026

Engineering Cell-permeable Protein

Engineering Cell-permeable Protein

Published on: December 28, 2009

The class of 2005. Germany: deciphering cellular processes.

Science (New York, N.Y.)

|October 22, 2005

Summary

Biochemist Anne Spang is advancing cell biology research with her new professorship at the Biozentrum in Basel. Her international career focuses on fundamental questions in cell biology.

Area of Science:

Cell Biology
Biochemistry

Background:

Anne Spang's international research career spans four countries.
Her work addresses fundamental questions in cell biology.

Purpose of the Study:

To highlight Anne Spang's appointment as a professor at the Biozentrum in Basel.
To summarize her research contributions to cell biology.

Main Methods:

Investigating fundamental cell biological processes.
Utilizing diverse research approaches across international collaborations.

Main Results:

Established a significant research program in cell biology.
Contributed to understanding core cellular mechanisms.

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Intracellular Refolding Assay

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Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging

Published on: December 2, 2016

Related Experiment Videos

Last Updated: Jul 6, 2026

Engineering Cell-permeable Protein

Engineering Cell-permeable Protein

Published on: December 28, 2009

Intracellular Refolding Assay

Intracellular Refolding Assay

Published on: January 24, 2012

Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging

Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging

Published on: December 2, 2016

Conclusions:

Anne Spang's expertise will enhance the Biozentrum's research capabilities.
Her work signifies progress in the field of cell biology.