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Updated: Aug 15, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Pacing for the prevention of atrial fibrillation
Anne M Gillis1, Charles R Kerr, Eugene Crystal
1University of Calgary, Calgary, Alberta. amgillis@ucalgary.ca
Insights
Atrial pacing effectively prevents atrial fibrillation (AF) in patients with symptomatic bradycardia. Minimizing ventricular pacing is crucial for AF prevention, especially in those with normal heart rhythm conduction.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Atrial fibrillation (AF) is a common arrhythmia.
- Symptomatic bradycardia necessitates cardiac pacing.
- Preventing AF is a key goal in cardiac pacing therapy.
Framework:
- Randomized clinical trials (RCTs) evaluate pacing strategies for AF prevention.
- Evidence links atrial pacing to reduced AF incidence in specific patient groups.
- Ventricular pacing burden correlates with AF risk.
Implementation:
- Atrial or dual-chamber pacing is beneficial for patients with symptomatic bradycardia and AF.
- Minimizing ventricular pacing is recommended for patients with intact AV conduction.
- Temporary atrial pacing may prevent perioperative AF after cardiac surgery.
Implications:
- Atrial pacing is not indicated for AF prevention in patients without bradycardia.
- Current selective pacing algorithms offer limited additional AF prevention benefits.
- Optimal atrial lead placement for AF prevention requires further investigation.
Abstract:
Multiple randomized clinical trials have demonstrated that atrial or dual-chamber pacing prevents paroxysmal and permanent atrial fibrillation (AF) in patients with symptomatic bradycardia as the primary indication for cardiac pacing. The benefit of atrial pacing for the prevention of AF is observed predominantly in patients with sinus node dysfunction. Emerging evidence also suggests that the risk of AF is directly linked to the proportion of time that ventricular pacing occurs. Consequently, pacemakers should be programmed to minimize the amount of ventricular pacing in patients with intrinsic atrioventricular conduction. Temporary atrial pacing following heart surgery may be of benefit for the prevention of perioperative AF. Atrial pacing has not been shown to prevent AF in patients without symptomatic bradycardia. In addition, selective pacing algorithms designed to prevent AF have minimal or no incremental benefits for the prevention of AF. At present, the role of selective atrial lead site(s) for the prevention of AF remains uncertain.
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