Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tumor microenvironment: what can effusions teach us?

Jareer Kassis1, Julius Klominek, Elise C Kohn

  • 1Molecular Signaling Section, Laboratory of Pathology, Center for Cancer Research National Cancer Institute, Bethesda, Maryland 20892-1500, USA.

Diagnostic Cytopathology
|October 22, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A case report of acute carcinoid heart failure during lutetium-177 dotatate-triapine treatment for well-differentiated neuroendocrine tumors.

Frontiers in oncology·2026
Same author

Ovarian cancer.

Nature reviews. Disease primers·2026
Same author

Approaches to optimize the benefits of immunotherapy and immunotherapy combinations across endometrial cancer types.

Journal of the National Cancer Institute·2026
Same author

Editorial: Latest advancements in organ-on-a-chip technology.

Frontiers in pharmacology·2025
Same author

How to optimize and evaluate diversity in gynecologic cancer clinical trials: statements from the GCIG Barcelona Meeting.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2025
Same author

A working group report from the 2024 National Cancer Institute / Gynecologic Cancer Steering Committee endometrial cancer clinical trials planning meeting: refining the approach to endometrial cancer in the immunotherapy era.

Journal of the National Cancer Institute·2025
Same journal

Pleural Fluid Cytology Detects Small Cell Carcinoma Transformation in EGFR-Mutant Lung Adenocarcinoma: A Case Report.

Diagnostic cytopathology·2026
Same journal

Clinical and Cytopathological Significance of Intracytoplasmic Lumina and Immunohistochemical Mucin Expression in Non-Muscle-Invasive Urothelial Carcinoma of the Bladder.

Diagnostic cytopathology·2026
Same journal

Pleural Effusion Cytology of Metastatic Sclerosing Epithelioid Fibrosarcoma.

Diagnostic cytopathology·2026
Same journal

Turnaround Time Trends in Cervical Cytology Screening in South Africa, 2005-2023.

Diagnostic cytopathology·2026
Same journal

Spontaneous Infarction of Benign Salivary Gland Tumors: A Series of 5 Cases.

Diagnostic cytopathology·2026
Same journal

Atypical Carcinoid Tumor Metastatic to the Parotid Gland: A Case Report and Review of the Literature.

Diagnostic cytopathology·2026
See all related articles

Malignant effusions, fluid collections containing cancer cells, are linked to poor prognosis. Understanding their unique tumor microenvironment is key to improving patient care and treatment strategies.

Area of Science:

  • Oncology
  • Cancer Biology
  • Pathology

Background:

  • Malignant effusions are unusual cancer manifestations with poor prognosis.
  • Neoplastic cells in effusions are metastatic, proliferative, and stimulate fluid buildup.
  • While treatments offer temporary relief, cures for malignant effusions are rare.

Purpose of the Study:

  • To investigate the tumor-cell microenvironment in malignant effusions.
  • To understand how the fluid microenvironment impacts cancer dissemination and progression.
  • To identify signaling activities and components within these effusions for better patient care.

Main Methods:

  • The abstract does not specify the methods used.
  • Further research is needed to dissect the signaling activity and components of malignant effusion microenvironments.

Related Experiment Videos

Main Results:

  • The abstract does not present specific results.
  • The fluid nature of the effusion microenvironment may significantly influence disease progression compared to solid tumors.

Conclusions:

  • Malignant effusions represent a critical area for biological, biochemical, and clinical study.
  • Understanding the unique microenvironment of malignant effusions is crucial for advancing cancer treatment and patient outcomes.