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Sleep and the gastrointestinal tract.
William C Orr1, Chien Lin Chen
1Lynn Health Science Institute, Oklahoma University Health Science Center, Oklahoma City, OK 73112, USA. worr@lhsi.net
Neurologic Clinics
|October 26, 2005
Summary
This review explores the link between gastrointestinal (GI) function and sleep, highlighting how sleep disturbances can worsen GI disorders like GERD and IBS. Understanding this connection is key to improving patient outcomes.
Area of Science:
- Gastroenterology
- Sleep Medicine
- Neurogastroenterology
Background:
- The interplay between gastrointestinal (GI) function and sleep is complex and bidirectional.
- Sleep disturbances are frequently reported in patients with GI disorders, suggesting a significant connection.
Purpose of the Study:
- To review the integration of GI functioning with sleep.
- To explore how this interaction contributes to sleep disorders and the pathogenesis of GI disorders.
Main Methods:
- Literature review integrating data on GI function, sleep, and related disorders.
- Analysis of studies examining sensory and autonomic functioning during sleep in GI patients.
Main Results:
- Sleep-related gastroesophageal reflux (GER) is implicated in esophagitis and respiratory complications.
- While some sensory functions decrease during sleep, visceral sensation may be enhanced, protecting against aspiration.
- Patients with functional bowel disorders report more sleep complaints, though sleep pattern abnormalities are inconsistent.
- Autonomic functioning during REM sleep may differentiate Irritable Bowel Syndrome (IBS) patients.
Conclusions:
- The relationship between sleep and GI functioning offers a new perspective on the pathophysiology of various GI disorders.
- Further research into sleep and GI interactions is crucial for understanding and managing these conditions.