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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Severe acute respiratory syndrome (SARS) in neonates and children
1Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, NT, Hong Kong, ROC.
Insights
Children with severe acute respiratory syndrome (SARS) experience a milder acute phase, with no reported deaths. Long-term monitoring is crucial for potential physical, psychological, and social issues.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Severe acute respiratory syndrome (SARS) presents differently in pediatric populations compared to adults.
- Understanding SARS in children is critical due to unique clinical presentations and outcomes.
Purpose of the Study:
- To review the current understanding of SARS coronavirus infection in newborns and children.
- To highlight the benign acute course and long-term sequelae in pediatric SARS cases.
Main Methods:
- Literature review of SARS cases in pediatric populations.
- Analysis of clinical presentation, transmission, and outcomes in children.
Main Results:
- SARS exhibits a more benign acute course in children, with no reported fatalities in the pediatric age group.
- Vertical transmission of SARS from mother to infant was not observed.
- Children may experience exercise impairment and radiological abnormalities six months post-diagnosis.
Conclusions:
- While the acute phase of SARS is milder in children, long-term sequelae require ongoing assessment and management.
- Standardized treatment protocols for pediatric SARS are lacking, often relying on adult-based approaches.
- Regular follow-up is essential to address physical, psychological, and social long-term effects in children recovering from SARS.
Abstract:
Severe acute respiratory syndrome (SARS) runs a more benign course in children during the acute phase. Infants born to mothers with the disease did not acquire the infection through vertical transmission. The treatment strategy for children with SARS has not been standardised and is based on adult experience. Thus far, no deaths have been reported in the paediatric age group. Exercise impairment and residual radiological abnormalities were present six months after diagnosis. It is important to assess these patients on a regular basis to detect and provide appropriate management for any persistent or emerging long term sequelae in the physical, psychological, and social domains. This review describes the current understanding of SARS coronavirus infection in newborns and children.
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